Probenecid is also used to prevent or treat other medical problems that may occur if too much uric acid is present in the body. Probenecid is sometimes used with certain kinds of antibiotics to make them more effective in the treatment of infections.
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You should drink plenty of water while taking probenecid. This will help flush the uric acid from your kidneys as the medication starts working.
This is especially important if:. Your healthcare professional may do blood tests to check your liver function while you are taking Probenecid. The most common side effects of Probenecid are liver problems, nausea, gout flares, joint pain, and rash. Contact your prescriber if any of these side effects occur. When you are taking Probenecid, it is very important that your doctors know if you are taking any other medicine. This includes prescription and non-prescription medicines as well as birth control pills, vitamins, and herbal supplements.
Gout may flare up when you start taking any medicine to lower your uric acid. This is caused when crystals begin to dissolve in your joints as your uric acid level goes down. Probenecid may help you prevent that excess uric acid build-up from causing crystals to form, settle in your joints, and cause painful gout attacks.
Probenecid comes in tablet form you take by mouth. Adults with chronic gout usually take mg of probenecid twice a day, and increase to mg two times per day and higher if necessary. Your doctor can watch how well the drug works for you and how well you tolerate it. Probenecid may take six months to a year to reach full effectiveness and prevent gout attacks. Your doctor may prescribe colchicine or an NSAID or a corticosteroid for you to treat acute gout symptoms during that time.
Drink six to eight full glasses of water or other fluids each day when you take probenecid. This helps you prevent kidney stones. Drinking enough water is a good habit if you have gout, so remind yourself to reach that goal every day. Do not take aspirin for a headache or joint pain while you take probenecid.
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