What is the difference between isotretinoin and tretinoin

The patient was hospitalized during induction treatment. She was able to finish the treatment course and achieved complete remission. The patient was discharged, and the following month, she returned to the outpatient infusion center to begin 10 cycles of intravenous IV chemotherapy. Tretinoin was to continue on an outpatient basis, along with IV chemotherapy per protocol. But instead of administering two day cycles of tretinoin as intended, an oncology clinic nurse enrolled the patient and prescriber in the iPledge program and called in a prescription for Claravis ISOtretinoin [cis retinoic acid]; other brands include Amnesteem, Myorisan, and Sotret to a local pharmacy.

The clinic nurse did not realize that tretinoin and ISOtretinoin were not the same medication. She was probably more familiar with ISOtretinoin because it is prescribed more frequently than tretinoin in many pediatric oncology centers. We have detected that you are using an Ad Blocker. PracticeUpdate is free to end users but we rely on advertising to fund our site. Please consider supporting PracticeUpdate by whitelisting us in your ad blocker.

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Close Back. Sign in. Join now. Follow us on:. Median Dermatology Life Quality Index scores showed significant improvement over time, again with no difference between the two groups. On histology, both groups displayed reductions in corneal layer thickness and elastosis, along with increased epidermal thickness; these changes were greater with time.

There was also a significant reduction in p53 expression and an increase in collagen I, with both changes being greater at 12 months than 6 months. Bagatin reported having no financial conflicts.

Skip to main content. Aesthetic Dermatology. By Bruce Jancin.